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<meta content="Edwards, Ashley" name="eprints.creators_name" />
<meta content="Jones, Susan M." name="eprints.creators_name" />
<meta content="Ashley.Edwards@utas.edu.au" name="eprints.creators_id" />
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<meta content="Peripheral (extragonadal) metabolism of the primary reproductive steroids, testosterone (T) and estradiol (E2), occurs in a variety of vertebrate body tissues. The primary steroids may be modified in two main ways: derivatisation to more biologically active forms, or conjugation to increase solubility. The molecular structures of these steroid metabolites vary between vertebrate classes. Such phyologenetic differences are of intrinsic evolutionary interest; furthermore some of these metabolites may function as semiochemicals, communicating location, reproductive condition and even synchronising mating behaviour in some species. However, such data is rare for reptiles. We have investigated and confirmed the occurrence of substantial peripheral steroid metabolism using in vitro incubations of tissues from the blue-tongued skink, Tiliqua nigrolutea. Additionally, we have demonstrated that the relative proportions of primary steroids undergoing each of these types of conversions vary with sex, reproductive condition and tissue type. This study has identified a group of steroid molecules that are potentially communicating information to conspecifics during the mating period." name="eprints.abstract" />
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<meta content="Peripheral (extragonadal) metabolism of the primary reproductive steroids, testosterone (T) and estradiol (E2), occurs in a variety of vertebrate body tissues. The primary steroids may be modified in two main ways: derivatisation to more biologically active forms, or conjugation to increase solubility. The molecular structures of these steroid metabolites vary between vertebrate classes. Such phyologenetic differences are of intrinsic evolutionary interest; furthermore some of these metabolites may function as semiochemicals, communicating location, reproductive condition and even synchronising mating behaviour in some species. However, such data is rare for reptiles. We have investigated and confirmed the occurrence of substantial peripheral steroid metabolism using in vitro incubations of tissues from the blue-tongued skink, Tiliqua nigrolutea. Additionally, we have demonstrated that the relative proportions of primary steroids undergoing each of these types of conversions vary with sex, reproductive condition and tissue type. This study has identified a group of steroid molecules that are potentially communicating information to conspecifics during the mating period." name="DC.description" />
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<h1 class="ep_tm_pagetitle">Peripheral conversion of steroids in a viviparous skink, Tiliqua nigrolutea</h1>
<p style="margin-bottom: 1em" class="not_ep_block"><span class="person_name">Edwards, Ashley</span> and <span class="person_name">Jones, Susan M.</span> (2000) <xhtml:em>Peripheral conversion of steroids in a viviparous skink, Tiliqua nigrolutea.</xhtml:em> In: ANZSCPB, 8-10 Dec 2000, deakin University, Geelong, Victoria, Australia. (Unpublished)</p><p style="margin-bottom: 1em" class="not_ep_block"></p><table style="margin-bottom: 1em" class="not_ep_block"><tr><td valign="top" style="text-align:center"><a onmouseover="EPJS_ShowPreview( event, 'doc_preview_672' );" href="http://eprints.utas.edu.au/660/1/Deakin_abstract.pdf" onmouseout="EPJS_HidePreview( event, 'doc_preview_672' );"><img alt="[img]" src="http://eprints.utas.edu.au/style/images/fileicons/application_pdf.png" class="ep_doc_icon" border="0" /></a><div class="ep_preview" id="doc_preview_672"><table><tr><td><img alt="" src="http://eprints.utas.edu.au/660/thumbnails/1/preview.png" class="ep_preview_image" border="0" /><div class="ep_preview_title">Preview</div></td></tr></table></div></td><td valign="top"><a href="http://eprints.utas.edu.au/660/1/Deakin_abstract.pdf"><span class="ep_document_citation">PDF</span></a> - Requires a PDF viewer<br />11Kb</td></tr></table><div class="not_ep_block"><h2>Abstract</h2><p style="padding-bottom: 16px; text-align: left; margin: 1em auto 0em auto">Peripheral (extragonadal) metabolism of the primary reproductive steroids, testosterone (T) and estradiol (E2), occurs in a variety of vertebrate body tissues. The primary steroids may be modified in two main ways: derivatisation to more biologically active forms, or conjugation to increase solubility. The molecular structures of these steroid metabolites vary between vertebrate classes. Such phyologenetic differences are of intrinsic evolutionary interest; furthermore some of these metabolites may function as semiochemicals, communicating location, reproductive condition and even synchronising mating behaviour in some species. However, such data is rare for reptiles. We have investigated and confirmed the occurrence of substantial peripheral steroid metabolism using in vitro incubations of tissues from the blue-tongued skink, Tiliqua nigrolutea. Additionally, we have demonstrated that the relative proportions of primary steroids undergoing each of these types of conversions vary with sex, reproductive condition and tissue type. This study has identified a group of steroid molecules that are potentially communicating information to conspecifics during the mating period.</p></div><table style="margin-bottom: 1em" cellpadding="3" class="not_ep_block" border="0"><tr><th valign="top" class="ep_row">Item Type:</th><td valign="top" class="ep_row">Conference or Workshop Item (Poster)</td></tr><tr><th valign="top" class="ep_row">Additional Information:</th><td valign="top" class="ep_row">conference poster</td></tr><tr><th valign="top" class="ep_row">Subjects:</th><td valign="top" class="ep_row"><a href="http://eprints.utas.edu.au/view/subjects/270604.html">270000 Biological Sciences > 270600 Physiology > 270604 Comparative Physiology</a><br /><a href="http://eprints.utas.edu.au/view/subjects/270603.html">270000 Biological Sciences > 270600 Physiology > 270603 Animal Physiology - Systems</a></td></tr><tr><th valign="top" class="ep_row">ID Code:</th><td valign="top" class="ep_row">660</td></tr><tr><th valign="top" class="ep_row">Deposited By:</th><td valign="top" class="ep_row"><span class="ep_name_citation"><span class="person_name">Dr Ashley Edwards</span></span></td></tr><tr><th valign="top" class="ep_row">Deposited On:</th><td valign="top" class="ep_row">24 Jan 2007</td></tr><tr><th valign="top" class="ep_row">Last Modified:</th><td valign="top" class="ep_row">09 Jan 2008 02:30</td></tr><tr><th valign="top" class="ep_row">ePrint Statistics:</th><td valign="top" class="ep_row"><a target="ePrintStats" href="/es/index.php?action=show_detail_eprint;id=660;">View statistics for this ePrint</a></td></tr></table><p align="right">Repository Staff Only: <a href="http://eprints.utas.edu.au/cgi/users/home?screen=EPrint::View&eprintid=660">item control page</a></p>
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