<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html> <head> <title>UTas ePrints - Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management</title> <script type="text/javascript" src="http://eprints.utas.edu.au/javascript/auto.js"><!-- padder --></script> <style type="text/css" media="screen">@import url(http://eprints.utas.edu.au/style/auto.css);</style> <style type="text/css" media="print">@import url(http://eprints.utas.edu.au/style/print.css);</style> <link rel="icon" href="/images/eprints/favicon.ico" type="image/x-icon" /> <link rel="shortcut icon" href="/images/eprints/favicon.ico" type="image/x-icon" /> <link rel="Top" href="http://eprints.utas.edu.au/" /> <link rel="Search" href="http://eprints.utas.edu.au/cgi/search" /> <meta content="Gartrell, Brett D." name="eprints.creators_name" /> <meta content="Raidal, Shane R." name="eprints.creators_name" /> <meta content="Jones, Susan M." name="eprints.creators_name" /> <meta name="eprints.creators_id" /> <meta name="eprints.creators_id" /> <meta content="S.M.Jones@utas.edu.au" name="eprints.creators_id" /> <meta content="article" name="eprints.type" /> <meta content="2007-02-22" name="eprints.datestamp" /> <meta content="2008-02-04T02:26:32Z" name="eprints.lastmod" /> <meta content="show" name="eprints.metadata_visibility" /> <meta content="Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management " name="eprints.title" /> <meta content="pub" name="eprints.ispublished" /> <meta content="270604" name="eprints.subjects" /> <meta content="300506" name="eprints.subjects" /> <meta content="restricted" name="eprints.full_text_status" /> <meta content="renal toxicosis; neurologic disease; alkaloids; swift parrots; Lathamus discolor " name="eprints.keywords" /> <meta content=" http://www.aav.org/" name="eprints.note" /> <meta content="This report details the investigation of renal disease associated with neurologic signs and deaths in a captive research colony of the endangered swift parrot (Lathamis discolor). The syndrome affected birds irregularly during 11 months from October 1999 to September 2000. Ten birds from 4 aviaries were clinically affected, and 9 birds died. The most common clinical signs were weight loss, neurologic dysfunction (ataxia and generalized tremors), and articular gout. At necropsy, common findings included gross nephropathy, visceral gout, and gonadal regression or inflammation. Histopathologic changes included renal tubular degeneration and accumulations of black crystals, assumed to be urates, in renal tubules and collecting ducts. These histopathologic changes are nonspecific and could be associated with a wide variety of nephrotoxins including, but not limited to, heavy metals, organic solvents, phenol, antibacterial agents, pesticides, and ethylene glycol. The syndrome was associated with the feeding of a high-protein diet and the presence of nestin, boxes and other environmental I-actors. A number of potentially toxic substances were found in the swift parrots' environment, including nitrate fertilizer, zinc from galvanized wire, and potentially toxic wood fragments (Tasmanian sassafras [Atherosperma moschatum]). However, not all affected birds were exposed to these toxins, or diagnostic testing ruled them Out of consideration. Regardless of the initial cause of renal damage, the overall renal pathologic changes were consistent with a urate nephropathy. There is still uncertainty as to the initial cause of the neurologic disease and renal damage despite the intensive investigtion described here. The immediate deterioration of 2 swift parrots after the reintroduction of the high-protein diet led us to suspect that dietary levels of protein might be a contributing factor to the renal disease. " name="eprints.abstract" /> <meta content="2003-12" name="eprints.date" /> <meta content="published" name="eprints.date_type" /> <meta content="Journal of Avian Medicine and Surgery" name="eprints.publication" /> <meta content="17" name="eprints.volume" /> <meta content="4" name="eprints.number" /> <meta content="213-223" name="eprints.pagerange" /> <meta content="10.1647/2002-001" name="eprints.id_number" /> <meta content="UNSPECIFIED" name="eprints.thesis_type" /> <meta content="TRUE" name="eprints.refereed" /> <meta content="1082-6742" name="eprints.issn" /> <meta content="http://dx.doi.org/10.1647/2002-001" name="eprints.official_url" /> <meta content="Gartrell, Brett D. and Raidal, Shane R. and Jones, Susan M. (2003) Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management. Journal of Avian Medicine and Surgery, 17 (4). pp. 213-223. ISSN 1082-6742" name="eprints.citation" /> <meta content="http://eprints.utas.edu.au/734/1/galleyrenal_dz_paper_1.pdf" name="eprints.document_url" /> <link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /> <meta content="Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management " name="DC.title" /> <meta content="Gartrell, Brett D." name="DC.creator" /> <meta content="Raidal, Shane R." name="DC.creator" /> <meta content="Jones, Susan M." name="DC.creator" /> <meta content="270604 Comparative Physiology" name="DC.subject" /> <meta content="300506 Pathology" name="DC.subject" /> <meta content="This report details the investigation of renal disease associated with neurologic signs and deaths in a captive research colony of the endangered swift parrot (Lathamis discolor). The syndrome affected birds irregularly during 11 months from October 1999 to September 2000. Ten birds from 4 aviaries were clinically affected, and 9 birds died. The most common clinical signs were weight loss, neurologic dysfunction (ataxia and generalized tremors), and articular gout. At necropsy, common findings included gross nephropathy, visceral gout, and gonadal regression or inflammation. Histopathologic changes included renal tubular degeneration and accumulations of black crystals, assumed to be urates, in renal tubules and collecting ducts. These histopathologic changes are nonspecific and could be associated with a wide variety of nephrotoxins including, but not limited to, heavy metals, organic solvents, phenol, antibacterial agents, pesticides, and ethylene glycol. The syndrome was associated with the feeding of a high-protein diet and the presence of nestin, boxes and other environmental I-actors. A number of potentially toxic substances were found in the swift parrots' environment, including nitrate fertilizer, zinc from galvanized wire, and potentially toxic wood fragments (Tasmanian sassafras [Atherosperma moschatum]). However, not all affected birds were exposed to these toxins, or diagnostic testing ruled them Out of consideration. Regardless of the initial cause of renal damage, the overall renal pathologic changes were consistent with a urate nephropathy. There is still uncertainty as to the initial cause of the neurologic disease and renal damage despite the intensive investigtion described here. The immediate deterioration of 2 swift parrots after the reintroduction of the high-protein diet led us to suspect that dietary levels of protein might be a contributing factor to the renal disease. " name="DC.description" /> <meta content="2003-12" name="DC.date" /> <meta content="Article" name="DC.type" /> <meta content="PeerReviewed" name="DC.type" /> <meta content="application/pdf" name="DC.format" /> <meta content="http://eprints.utas.edu.au/734/1/galleyrenal_dz_paper_1.pdf" name="DC.identifier" /> <meta content="http://dx.doi.org/10.1647/2002-001" name="DC.relation" /> <meta content="Gartrell, Brett D. and Raidal, Shane R. and Jones, Susan M. (2003) Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management. Journal of Avian Medicine and Surgery, 17 (4). pp. 213-223. 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management</h1> <p style="margin-bottom: 1em" class="not_ep_block"><span class="person_name">Gartrell, Brett D.</span> and <span class="person_name">Raidal, Shane R.</span> and <span class="person_name">Jones, Susan M.</span> (2003) <xhtml:em>Renal disease in captive swift parrots (Lathamus discolor): Clinical findings and disease management.</xhtml:em> Journal of Avian Medicine and Surgery, 17 (4). pp. 213-223. ISSN 1082-6742</p><p style="margin-bottom: 1em" class="not_ep_block"></p><table style="margin-bottom: 1em" class="not_ep_block"><tr><td valign="top" style="text-align:center"><a href="http://eprints.utas.edu.au/734/1/galleyrenal_dz_paper_1.pdf"><img alt="[img]" src="http://eprints.utas.edu.au/style/images/fileicons/application_pdf.png" class="ep_doc_icon" border="0" /></a></td><td valign="top"><a href="http://eprints.utas.edu.au/734/1/galleyrenal_dz_paper_1.pdf"><span class="ep_document_citation">PDF</span></a> - Full text restricted - Requires a PDF viewer<br />346Kb</td><td><form method="get" accept-charset="utf-8" action="http://eprints.utas.edu.au/cgi/request_doc"><input accept-charset="utf-8" value="743" name="docid" type="hidden" /><div class=""><input value="Request a copy" name="_action_null" class="ep_form_action_button" onclick="return EPJS_button_pushed( '_action_null' )" type="submit" /> </div></form></td></tr></table><p style="margin-bottom: 1em" class="not_ep_block">Official URL: <a href="http://dx.doi.org/10.1647/2002-001">http://dx.doi.org/10.1647/2002-001</a></p><div class="not_ep_block"><h2>Abstract</h2><p style="padding-bottom: 16px; text-align: left; margin: 1em auto 0em auto">This report details the investigation of renal disease associated with neurologic signs and deaths in a captive research colony of the endangered swift parrot (Lathamis discolor). The syndrome affected birds irregularly during 11 months from October 1999 to September 2000. Ten birds from 4 aviaries were clinically affected, and 9 birds died. The most common clinical signs were weight loss, neurologic dysfunction (ataxia and generalized tremors), and articular gout. At necropsy, common findings included gross nephropathy, visceral gout, and gonadal regression or inflammation. Histopathologic changes included renal tubular degeneration and accumulations of black crystals, assumed to be urates, in renal tubules and collecting ducts. These histopathologic changes are nonspecific and could be associated with a wide variety of nephrotoxins including, but not limited to, heavy metals, organic solvents, phenol, antibacterial agents, pesticides, and ethylene glycol. The syndrome was associated with the feeding of a high-protein diet and the presence of nestin, boxes and other environmental I-actors. A number of potentially toxic substances were found in the swift parrots' environment, including nitrate fertilizer, zinc from galvanized wire, and potentially toxic wood fragments (Tasmanian sassafras [Atherosperma moschatum]). However, not all affected birds were exposed to these toxins, or diagnostic testing ruled them Out of consideration. Regardless of the initial cause of renal damage, the overall renal pathologic changes were consistent with a urate nephropathy. There is still uncertainty as to the initial cause of the neurologic disease and renal damage despite the intensive investigtion described here. The immediate deterioration of 2 swift parrots after the reintroduction of the high-protein diet led us to suspect that dietary levels of protein might be a contributing factor to the renal disease. </p></div><table style="margin-bottom: 1em" cellpadding="3" class="not_ep_block" border="0"><tr><th valign="top" class="ep_row">Item Type:</th><td valign="top" class="ep_row">Article</td></tr><tr><th valign="top" class="ep_row">Additional Information:</th><td valign="top" class="ep_row"> http://www.aav.org/</td></tr><tr><th valign="top" class="ep_row">Keywords:</th><td valign="top" class="ep_row">renal toxicosis; neurologic disease; alkaloids; swift parrots; Lathamus discolor </td></tr><tr><th valign="top" class="ep_row">Subjects:</th><td valign="top" class="ep_row"><a href="http://eprints.utas.edu.au/view/subjects/270604.html">270000 Biological Sciences > 270600 Physiology > 270604 Comparative Physiology</a><br /><a href="http://eprints.utas.edu.au/view/subjects/300506.html">300000 Agricultural, Veterinary and Environmental Sciences > 300500 Veterinary Sciences > 300506 Pathology</a></td></tr><tr><th valign="top" class="ep_row">Collections:</th><td valign="top" class="ep_row">UNSPECIFIED</td></tr><tr><th valign="top" class="ep_row">ID Code:</th><td valign="top" class="ep_row">734</td></tr><tr><th valign="top" class="ep_row">Deposited By:</th><td valign="top" class="ep_row"><span class="ep_name_citation"><span class="person_name">A/Prof. Susan M. Jones</span></span></td></tr><tr><th valign="top" class="ep_row">Deposited On:</th><td valign="top" class="ep_row">22 Feb 2007</td></tr><tr><th valign="top" class="ep_row">Last Modified:</th><td valign="top" class="ep_row">04 Feb 2008 13:26</td></tr><tr><th valign="top" class="ep_row">ePrint Statistics:</th><td valign="top" class="ep_row"><a target="ePrintStats" href="/es/index.php?action=show_detail_eprint;id=734;">View statistics for this ePrint</a></td></tr></table><p align="right">Repository Staff Only: <a href="http://eprints.utas.edu.au/cgi/users/home?screen=EPrint::View&eprintid=734">item control page</a></p> </td></tr></table> </div> <!-- InstanceEndEditable --></td> </tr> <tr> <td><!-- #BeginLibraryItem "/Library/footer_eprints.lbi" --> <table width="795" border="0" align="left" cellpadding="0" class="footer"> <tr valign="top"> <td colspan="2"><div align="center"><a href="http://www.utas.edu.au">UTAS home</a> | <a href="http://www.utas.edu.au/library/">Library home</a> | <a href="/">ePrints home</a> | <a href="/contact.html">contact</a> | <a href="/information.html">about</a> | <a href="/view/">browse</a> | <a href="/perl/search/simple">search</a> | <a href="/perl/register">register</a> | <a href="/perl/users/home">user area</a> | <a href="/help/">help</a></div><br /></td> </tr> <tr><td colspan="2"><p><img src="/images/eprints/footerline.gif" width="100%" height="4" /></p></td></tr> <tr valign="top"> <td width="68%" class="footer">Authorised by the University Librarian<br /> © University of Tasmania ABN 30 764 374 782<br /> <a href="http://www.utas.edu.au/cricos/">CRICOS Provider Code 00586B</a> | <a href="http://www.utas.edu.au/copyright/copyright_disclaimers.html">Copyright & Disclaimers</a> | <a href="http://www.utas.edu.au/accessibility/index.html">Accessibility</a> | <a href="http://eprints.utas.edu.au/feedback/">Site Feedback</a> </td> <td width="32%"><div align="right"> <p align="right" class="NoPrint"><a href="http://www.utas.edu.au/"><img src="http://www.utas.edu.au/shared/logos/unioftasstrip.gif" alt="University of Tasmania Home Page" width="260" height="16" border="0" align="right" /></a></p> <p align="right" class="NoPrint"><a href="http://www.utas.edu.au/"><br /> </a></p> </div></td> </tr> <tr valign="top"> <td><p> </p></td> <td><div align="right"><span class="NoPrint"><a href="http://www.eprints.org/software/"><img src="/images/eprintslogo.gif" alt="ePrints logo" width="77" height="29" border="0" align="bottom" /></a></span></div></td> </tr> </table> <!-- #EndLibraryItem --> <div align="center"></div></td> </tr> </table> </body> </html>