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<title>UTas ePrints - Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry</title>
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<meta content="van der Mei, I.A.F." name="eprints.creators_name" />
<meta content="Blizzard, Leigh" name="eprints.creators_name" />
<meta content="Stankovich, James" name="eprints.creators_name" />
<meta content="Ponsonby, A-L." name="eprints.creators_name" />
<meta content="Dwyer, T." name="eprints.creators_name" />
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<meta content="2007-04-02" name="eprints.datestamp" />
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<meta content="Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry
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<meta content="321202" name="eprints.subjects" />
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<meta content="Melanin; skin type; body hair; seasonal variation; misclassification; spectrophotometry" name="eprints.keywords" />
<meta content="Recent advances have enabled quite accurate estimation of cutaneous melanin density by spectrophotometry using reflectance of light at wavelengths 400 and 420 nm. Our purpose was to assess the effect of body hair and seasonal variation at the upper inner arm and buttock on measurements of melanin density. We estimated melanin density of 104 volunteers at three-monthly intervals over 12 months both before and after shaving. Removing body hair at the upper inner arm had no effect, but substantially reduced melanin estimates at the buttock in men. Significant seasonal variation was only observed at the upper inner arm, with highest readings in summer-autumn. In case-control studies, misclassification due to body hair at the buttock and seasonal variation at the upper inner arm could affect the observed odds ratio substantially. However, both sources of error can be reduced by careful attention to key aspects of study design." name="eprints.abstract" />
<meta content="2002" name="eprints.date" />
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<meta content="Journal of Photochemistry and Photobiology B: Biology" name="eprints.publication" />
<meta content="68" name="eprints.volume" />
<meta content="45-52" name="eprints.pagerange" />
<meta content="10.1016/S1011-1344(02)00331-7" name="eprints.id_number" />
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<meta content="1011-1344" name="eprints.issn" />
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<meta content="[1] D.M. Parkin, S.L. Whelan, J. Ferlay, L. Raymond, J. Young (eds). Cancer Incidence in Five Continents Vol VII. IARC Scientific Publicatios No 143. Lyon: International Agency for Research on Cancer, 1997.
[2] J.M. Bliss, D. Ford, A.J. Swerdlow, B.K. Armstrong, M. Cristofolini, J.M. Elwood, A. Green, E.A. Holly, T. Mack, R. MacKie, A. Østerlind, S.D. Walter, J. Peto, D.F. Easton. Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: systematic overview of 10 case-control studies. Int. J. Cancer 62 (1995) 367-76.
[3] A. Kricker, B.K. Armstrong, D.R. English. Sun exposure and non-melanocytic skin cancer. Cancer Causes Control 5 (1994) 367-92.
[4] T. Dwyer, K.H. Muller, L. Blizzard, R. Ashbolt, G. Phillips. The use of melanin spectrophotometry to estimate melanin density in Caucasians. Cancer Epidemiol. Biomarkers Prev. 7 (1998) 203-6.
[5] T. Dwyer, G. Prota, L. Blizzard, R. Ashbolt, M.R. Vincensi. Melanin density and melanin type predict melanocytic naevi in 19–20 year olds of northern European ancestry. Melanoma Res. 10 (2000) 387-94.
[6] A. Green, R. MacLennan, V. Siskind. Common acquired naevi and the risk of malignant melanoma. Int. J. Cancer 35 (1985) 297-300.
[7] T. Dwyer, L. Blizzard, R. Ashbolt, J. Plumb, M. Berwick, J.M. Stankovich. Cutaneous melanin density measured by spectrophotometry and risk of malignant melanoma, basal cell carcinoma and squamous cell carcinoma of the skin. Am. J. Epidemiol. 155 (2002) 614-621.
[8] G.W. Lasker. Seasonal changes in skin colour. Am. J. Phys. Anthropol. 12 (1954) 553-7.
[9] J. Lock-Andersen, H.C. Wulf. Seasonal variation of skin pigmentation. Acta. Derm. Venereol. 77 (1997) 219-21.
[10] P.E. Shrout, J.L. Fleiss. Intraclass correlations: Uses in assessing rater reliability. Psychol. Bull. 86 (1979) 420-8.
[11] N. Kollias, A.H. Baqer. Quantitative assessment of UV-induced pigmentation and erythema. Photodermatology 5 (1988) 53-60.
[12] N.G. Jablonski, G. Chaplin. The evolution of human skin coloration. J. Hum. Evol. 39 (2000) 57-106.
[13] M.D. Shriver, E.J. Parra. Comparison of narrow-band reflectance spectroscopy and tristimulus colorimetry for measurements of skin and hair color in persons of different biological ancestry. Am. J. Phys. Anthropol. 112 (2000) 17-27.
[14] A. Green, N.G. Martin. Measurement and perception of skin colour in a skin cancer survey. Br. J. Dermatol. 123 (1990) 77-84.
[15] P. Clark, A.E. Stark, R.J. Walsh, R. Jardine, N.G. Martin. A twin study of skin reflectance. Ann. Hum. Biol. 8 (1981) 529-41.
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<meta content="van der Mei, I.A.F. and Blizzard, Leigh and Stankovich, James and Ponsonby, A-L. and Dwyer, T. (2002) Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry. Journal of Photochemistry and Photobiology B: Biology, 68 . pp. 45-52. ISSN 1011-1344" name="eprints.citation" />
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" name="DC.title" />
<meta content="van der Mei, I.A.F." name="DC.creator" />
<meta content="Blizzard, Leigh" name="DC.creator" />
<meta content="Stankovich, James" name="DC.creator" />
<meta content="Ponsonby, A-L." name="DC.creator" />
<meta content="Dwyer, T." name="DC.creator" />
<meta content="321202 Epidemiology" name="DC.subject" />
<meta content="Recent advances have enabled quite accurate estimation of cutaneous melanin density by spectrophotometry using reflectance of light at wavelengths 400 and 420 nm. Our purpose was to assess the effect of body hair and seasonal variation at the upper inner arm and buttock on measurements of melanin density. We estimated melanin density of 104 volunteers at three-monthly intervals over 12 months both before and after shaving. Removing body hair at the upper inner arm had no effect, but substantially reduced melanin estimates at the buttock in men. Significant seasonal variation was only observed at the upper inner arm, with highest readings in summer-autumn. In case-control studies, misclassification due to body hair at the buttock and seasonal variation at the upper inner arm could affect the observed odds ratio substantially. However, both sources of error can be reduced by careful attention to key aspects of study design." name="DC.description" />
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<h1 class="ep_tm_pagetitle">Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry</h1>
<p style="margin-bottom: 1em" class="not_ep_block"><span class="person_name">van der Mei, I.A.F.</span> and <span class="person_name">Blizzard, Leigh</span> and <span class="person_name">Stankovich, James</span> and <span class="person_name">Ponsonby, A-L.</span> and <span class="person_name">Dwyer, T.</span> (2002) <xhtml:em>Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry.</xhtml:em> Journal of Photochemistry and Photobiology B: Biology, 68 . pp. 45-52. ISSN 1011-1344</p><p style="margin-bottom: 1em" class="not_ep_block"></p><table style="margin-bottom: 1em" class="not_ep_block"><tr><td valign="top" style="text-align:center"><a href="http://eprints.utas.edu.au/890/1/van_der_Mei_JPhotochemPhotobiol2002.pdf"><img alt="[img]" src="http://eprints.utas.edu.au/style/images/fileicons/application_pdf.png" class="ep_doc_icon" border="0" /></a></td><td valign="top"><a href="http://eprints.utas.edu.au/890/1/van_der_Mei_JPhotochemPhotobiol2002.pdf"><span class="ep_document_citation">PDF</span></a> - Full text restricted - Requires a PDF viewer<br />574Kb</td></tr></table><p style="margin-bottom: 1em" class="not_ep_block">Official URL: <a href="http://dx.doi.org/10.1016/S1011-1344(02)00331-7">http://dx.doi.org/10.1016/S1011-1344(02)00331-7</a></p><div class="not_ep_block"><h2>Abstract</h2><p style="padding-bottom: 16px; text-align: left; margin: 1em auto 0em auto">Recent advances have enabled quite accurate estimation of cutaneous melanin density by spectrophotometry using reflectance of light at wavelengths 400 and 420 nm. Our purpose was to assess the effect of body hair and seasonal variation at the upper inner arm and buttock on measurements of melanin density. We estimated melanin density of 104 volunteers at three-monthly intervals over 12 months both before and after shaving. Removing body hair at the upper inner arm had no effect, but substantially reduced melanin estimates at the buttock in men. Significant seasonal variation was only observed at the upper inner arm, with highest readings in summer-autumn. In case-control studies, misclassification due to body hair at the buttock and seasonal variation at the upper inner arm could affect the observed odds ratio substantially. However, both sources of error can be reduced by careful attention to key aspects of study design.</p></div><table style="margin-bottom: 1em" cellpadding="3" class="not_ep_block" border="0"><tr><th valign="top" class="ep_row">Item Type:</th><td valign="top" class="ep_row">Article</td></tr><tr><th valign="top" class="ep_row">Keywords:</th><td valign="top" class="ep_row">Melanin; skin type; body hair; seasonal variation; misclassification; spectrophotometry</td></tr><tr><th valign="top" class="ep_row">Subjects:</th><td valign="top" class="ep_row"><a href="http://eprints.utas.edu.au/view/subjects/321202.html">320000 Medical and Health Sciences > 321200 Public Health and Health Services > 321202 Epidemiology</a></td></tr><tr><th valign="top" class="ep_row">ID Code:</th><td valign="top" class="ep_row">890</td></tr><tr><th valign="top" class="ep_row">Deposited By:</th><td valign="top" class="ep_row"><span class="ep_name_citation"><span class="person_name">Dr Ingrid A F van der Mei</span></span></td></tr><tr><th valign="top" class="ep_row">Deposited On:</th><td valign="top" class="ep_row">02 Apr 2007</td></tr><tr><th valign="top" class="ep_row">Last Modified:</th><td valign="top" class="ep_row">09 Jan 2008 02:30</td></tr><tr><th valign="top" class="ep_row">ePrint Statistics:</th><td valign="top" class="ep_row"><a target="ePrintStats" href="/es/index.php?action=show_detail_eprint;id=890;">View statistics for this ePrint</a></td></tr></table><p align="right">Repository Staff Only: <a href="http://eprints.utas.edu.au/cgi/users/home?screen=EPrint::View&eprintid=890">item control page</a></p>
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