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  5. <title>UTas ePrints - Detection and mapping of QTL on bovine chromosomes 2 and 5 segregating for live weight, average daily gain and body measurements in Japanese Black Cattle</title>
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  13. <meta content="Malau-Aduli, A.E.O." name="eprints.creators_name" />
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  29. <meta content="Detection and mapping of QTL on bovine
  30. chromosomes 2 and 5 segregating for live weight,
  31. average daily gain and body measurements in
  32. Japanese Black Cattle" name="eprints.title" />
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  34. <meta content="270200" name="eprints.subjects" />
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  42. <meta content="QTL mapping, Japanese Black cattle, BTA2, BTA5, body measurements, live weight, daily gain." name="eprints.keywords" />
  43. <meta content="Bovine chromosomes 2 (BTA2) and 5 (BTA5) of purebred, half-sib progeny sired by five Japanese black
  44. bulls were genotyped using microsatellite DNA markers. The data were subjected to linkage analysis for
  45. the detection and mapping of segregating quantitative trait loci (QTL) influencing live weight, average
  46. daily gain and body measurements at weaning. Probability coefficients of inheriting allele 1 or 2 from the
  47. sire at specific chromosomal intervals were computed. The phenotypic data on progeny were regressed on
  48. these probability coefficients in a within-common-parent regression analysis. Fixed effects of sex, parity
  49. and season of birth as well as age as a covariate, were fitted in a linear model to the phenotypic data and
  50. subsequently analysed using QTL Express by generating an F-statistic through permutation tests at
  51. chromosome-wide significance thresholds over 10, 000 iterations at 1 cM intervals. Highly significant
  52. (P<0.01) segregating QTL for body measurements were detected on BTA2 for hip width (1 cM) and chest
  53. depth (8 cM) in Sire Family 1 and pin bone width (16 cM) in Sire Family 3. Other significant QTL (P<0.05)
  54. detected were withers height (3 cM), hip height (4 cM), body length (4 cM), shoulder width (6 cM), lumbar
  55. width (3 cM), thurl width (3 cM) and canon circumference (2 cM) in Sire Family 1, shoulder width (16 cM) in
  56. Sire Family 3 and thurl width (24 cM), pin bone width (19 cM), heart girth (26 cM) and abdominal width (69
  57. cM) in Sire Family 4. Significant (P<0.05) QTL for live weight and average daily gain were detected on BTA2
  58. for birth weight (5 cM) and weaning weight (3 cM) in Sire Family 1 and post-weaning average daily gain (68
  59. cM) in Sire Family 4. BTA 5 contained QTL for birth weight, pin bone width and heart girth in Sire Family 3
  60. that were only suggestive and not significant. Such localization of economically important QTL as
  61. demonstrated in this study, will expedite genetic improvement via marker-assisted selection, gene
  62. introgression and positional cloning in Japanese black cattle." name="eprints.abstract" />
  63. <meta content="2007" name="eprints.date" />
  64. <meta content="published" name="eprints.date_type" />
  65. <meta content="Journal of Cell and Animal Biology" name="eprints.publication" />
  66. <meta content="1" name="eprints.volume" />
  67. <meta content="3" name="eprints.number" />
  68. <meta content="034-043" name="eprints.pagerange" />
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  70. <meta content="1996-0867" name="eprints.issn" />
  71. <meta content="http://www.academicjournals.org/JCAB/contents/2007cont/Oct.htm" name="eprints.official_url" />
  72. <meta content="Allan MF, Thallman RM, Cushman RA, Echternkamp SE, White SN,
  73. Kuehn LA, Casas E, Smith TPL (2007). Association of a single
  74. nucleotide polymorphism in SPP1 with growth traits and twinning in a
  75. cattle population selected for twinning rate. J. Anim. Sci. 85:341-347.
  76. Casas E, Keele JW, Shackleford SD, Stone RT, Koohmaraie M,
  77. Sonstegard TS, Smith TPL (1998). Association of the muscle
  78. hypertrophy locus with carcass traits in beef cattle. J. Anim. Sci. 76:
  79. 468-473.
  80. Casas E, Shackleford SD, Keele JW, Koohmaraie M, Smith TPL, Stone
  81. RT (2003). Detection of quantitative trait loci for growth and carcass
  82. composition in cattle. J. Anim. Sci. 81: 2976-2983.
  83. Casas E, Shackleford SD, Keele JW, Stone RT, Kappes SM,
  84. Koohmaraie M (2000). Quantitative trait loci affecting growth and
  85. carcass composition of cattle segregating alternate forms of myostatin.
  86. J. Anim. Sci. 78: 560-569.
  87. Casas E, Stone RT (2006). Putative quantitative trait loci associated
  88. with the probability of contracting infectious bovine keratoconjunctivitis.
  89. J. Anim. Sci. 84: 3180-3184.
  90. Casas E, White SN, Riley DG, Smith TPL, Brenneman RA, Olson TA,
  91. Johnson DD, Coleman SW, Bennett GL, Chase Jr CC (2005).
  92. Assessment of single nucleotide polymorphisms in genes residing on
  93. chromosomes 14 and 29 for association with carcass composition
  94. traits in Bos indicus cattle. J. Anim. Sci. 83: 13-19.
  95. Casas E, White SN, Shackelford SD, Wheeler TL, Koohmaraie M,
  96. Bennett GL, Smith TPL (2007). Assessing association of single
  97. nucleotide polymorphisms at the thyroglobulin gene with carcass
  98. traits in beef cattle. J. Anim. Sci. 85: 0179v1
  99. Churchill GA, Doerge RW (1994). Empirical threshold values for quantitative
  100. trait mapping. Genet. 138: 963-971.
  101. Davis GP, Hetzel DJS, Corbet NJ, Scacheri S, Lowden S, Renaud J,
  102. Mayne C, Stevenson R, Moore SS, Byrne K (1998).The mapping of
  103. quantitative trait loci for birth weight in a tropical beef herd. Proc. 6th
  104. Wld. Congr. Genet. Appl. Livest. Prod. 26: 441-444.
  105. De Koning DJ, Schulmant NF, Elo K, Moisio S, Kinos R, Vilkki J, Maki-
  106. Tanila A (2001). Mapping of multiple quantitative trait loci by simple
  107. regression in half-sib designs. J. Anim. Sci. 79: 616-622.
  108. De Koning DJ, Visscher PM, Knott SA, Haley CS (1998). A strategy for
  109. QTL detection in half-sib populations. Anim. Sci. 67: 257-268.
  110. Dekkers JCM (2004). Commercial application of marker- and geneassisted
  111. selection in livestock: Strategies and lessons. J. Anim. Sci.
  112. 82 (E. Suppl.): E313–E328.
  113. Doerge RW, Churchill GA (1996). Permutation tests for multiple loci
  114. affecting a quantitative character. Genet. 142: 285-294.
  115. Georges M, Dietz AB, Mishra A, Nielsen D, Sargent LS, Sorensen A,
  116. Steele MR, Zhao X, Leipold H, Womack JE, Lathrop M (1993).
  117. Microsatellite mapping of the gene causing weaver disease in cattle
  118. will allow the study an associated quantitative trait locus. Proc. Natl.
  119. Acad. Sci. U.S.A. 90: 1058-1062.
  120. Grosz MD, MacNeil MD (2001). Putative quantitative trait locus affecting
  121. birth weight on bovine chromosome 2. J. Anim. Sci. 79: 68-72.
  122. Haley CS, Knott SA (1992). A simple regression method for mapping
  123. quantitative trait loci in line crosses using flanking markers. Genetics
  124. 132: 1211-1222.
  125. Kappes SM, Keele JW, Stone RT, McGraw RA, Sonstegard TS, Smith
  126. TPL, Lopez-Corrales NL, Beattie CW (1997). A second generation
  127. linkage map of the bovine genome. Genome Res. 7: 235-249.
  128. Kim JJ, Farnir F, Taylor JF (2003). Detection of quantitative trait loci for
  129. growth and beef carcass fatness traits in a cross between Bos taurus
  130. (Angus) and Bos indicus (Brahman) cattle. J. Anim. Sci. 81: 1933-
  131. 1942.
  132. Kitamura C, Yasuda Y, Kobayashi T, Nomura T, Shimada K (1999).
  133. Genetic analysis of direct and maternal effects for calf market and
  134. carcass weights in Japanese Black cattle. Asian-Aust. J. Anim. Sci.
  135. 12: 843-845.
  136. Kneeland J, Li C, Basarab J, Snelling WM, Benkel B, Murdoch B,
  137. Hansen C, Moore SS (2004). Identification and fine mapping of
  138. quantitative trait loci for growth traits on bovine chromosomes 2, 6, 14,
  139. 19, 21 and 23 within one commercial line of Bos taurus. J. Anim. Sci.
  140. 82: 3405-3414.
  141. Knott SA, Elsen JM, Haley CS (1996). Methods for multiple markers
  142. mapping of quantitative trait loci in half-sib populations. Theoret. Appl.
  143. Genet. 93: 71-80.
  144. Li C, Basarab J, Snelling WM, Benkel B, Kneeland J, Murdoch B, Hansen
  145. C, Moore SS (2004a). Identification and fine mapping of quantitative
  146. trait loci for backfat on bovine chromosomes 2, 5, 6, 19, 21 and
  147. 23 in a commercial line of Bos taurus. J. Anim. Sci. 82: 967-972.
  148. Li C, Basarab J, Snelling WM, Benkel B, Murdoch B, Hansen C, Moore
  149. SS (2004b). Assessment of positional candidate genes myf5 and igf1
  150. for growth on bovine chromosome 5 in commercial lines of Bos
  151. taurus. J. Anim. Sci. 82: 1-7.
  152. Li C, Basarab J, Snelling WM, Benke B, Murdoch B, Moore SS (2002).
  153. The identification of common haplotypes on bovine chromosome 5
  154. within commercial lines of Bos taurus and their associations with
  155. growth traits. J. Anim. Sci. 80: 1187-1194.
  156. Lusk JL (2007). Association of single nucleotide polymorphisms in the
  157. leptin gene with body weight and backfat growth curve parameters for
  158. beef cattle. J. Anim Sci. 85:1865-1872.
  159. Macneil MD, Grosz MD (2002). Genome-wide scans for QTL affecting
  160. carcass traits in Hereford x composite double backcross populations.
  161. J. Anim. Sci. 80: 2316-2324.
  162. Malau-Aduli AEO, Aziz MA, Kojima T, Niibayashi T, Oshima K, Komatsu
  163. M (2004a). Fixing collinearity instability using principal component
  164. and ridge regression analyses in the relationship between body
  165. measurements and body weight in Japanese Black cattle. J. Anim.
  166. Vet. Adv. 3: 856-863.
  167. Malau-Aduli AEO, Niibayashi T, Kojima T, Oshima K, Komatsu M
  168. (2003a). Genome-wide scanning for QTL: Mapping methodology and
  169. detected QTL in cattle. J. Anim. Genet. 30:3-16.
  170. Malau-Aduli AEO, Niibayashi T, Kojima T, Oshima K, Mizoguchi Y,
  171. Komatsu M (2005a). Mapping the quantitative trait loci (QTL) for body
  172. shape and conformation measurements on BTA1 in Japanese Black cattle. Anim. Sci. J. 76: 19-27.
  173. Malau-Aduli AEO, Niibayashi T, Kojima T, Oshima K, Mizoguchi Y,
  174. Komatsu M (2005b). Interval mapping of growth quantitative trait loci
  175. in Japanese Black beef cattle using microsatellite DNA markers and
  176. half-sib regression analysis. Anim. Sci. J. 76: 11-18.
  177. Malau-Aduli AEO, Niibayashi T, Kojima T, Oshima K, Mizoguchi Y,
  178. Sugimoto Y, Komatsu M (2003b). Microsatellite DNA marker mapping
  179. of bovine chromosome one for QTL affecting birth weight and
  180. preweaning growth in Japanese Black cattle (Wagyu). In: Linda
  181. Hygate (Editor). 50 years of DNA. Proc. Assoc. Advance. Anim.
  182. Breed. Genet. 15: 14-17.
  183. Malau-Aduli AEO, Nishimura-Abe A, Niibayashi T, Yasuda Y, Kojima T,
  184. Abe S, Oshima K, Hasegawa K, Komatsu M (2004b). Mitochondrial
  185. DNA polymorphism, maternal lineage and correlations with postnatal
  186. growth of Japanese Black beef cattle to yearling age. Asian-Aust. J.
  187. Anim. Sci. 17: 1484-1490.
  188. Mizoshita K, Watanabe T, Hayashi H, Kubota C, Yamakuchi H,
  189. Todoroki J, Sugimoto Y (2004). Quantitative trait loci analysis for
  190. growth and carcass traits in a half-sib family of purebred Japanese
  191. Black (Wagyu) cattle. J. Anim. Sci. 82: 3415-3420.
  192. Mukai F, Oyama K, Kohno S (1995). Genetic relationships between
  193. performance test traits and field carcass traits in Japanese Black
  194. cattle. Livest. Prod. Sci. 44: 199-205.
  195. Mukai F, Sadahira M, Yoshimura T (2004). Comparison of carcass
  196. composition among Japanese Black, Holstein and their crossbred
  197. steers fattening on-farm. Anim. Sci. J. 75: 393-399.
  198. Mukai F, Yamagami A, Anada K (2000). Estimation of genetic parameters
  199. and trends for additive, direct maternal genetic effects for birth
  200. and calf market weights in Japanese Black beef cattle. Anim. Sci. J.
  201. 71: 462-469.
  202. Napolitano F, Catillo G, Lucioli S, Carretta A, Di Giacomo A, Rossi G,
  203. Moioli BM (2001). Evidence for quantitative trait locus for conformation
  204. traits on chromosome 19 in beef cattle. J. Anim. Breed. Genet.
  205. 118: 119-124.
  206. Napolitano F , Leone P, Puppo S, Moioli BM, Pilla F, Comincini S,
  207. Ferretti L, Carretta A (1996). Exploitation of microsatellites as genetic
  208. markers of beef performance traits in Piemontese x Chianina crossbred
  209. cattle. J. Anim. Breed. Genet. 113: 157-162.
  210. Nkrumah JD, Li C, Yu J, Hansen C, Keisler DH, Moore SS (2005).
  211. Polymorphisms in the bovine leptin promoter associated with serum
  212. leptin concentration, growth, feed intake, feeding behaviour, and
  213. measures of carcass merit. J. Anim. Sci. 83: 20-28.
  214. Oyama K, Mukai F, Yoshimura T (1996). Genetic relationships among
  215. traits recorded at registry judgement, reproductive traits of breeding
  216. females and carcass traits of fattening animals in Japanese Black
  217. cattle. Anim. Sci. Technol. (Japan) 67: 511-518.
  218. Rincker CB, Pyatt NA, Berger LL, Faulkner DB (2006). Relationship
  219. among GeneSTAR marbling marker, intramuscular fat deposition,
  220. and expected progeny differences in early weaned Simmental steers.
  221. J. Anim. Sci. 84: 686-693.
  222. Sambrook J, Fritsch EF, Maniatis T (1989). Molecular cloning. A
  223. laboratory manual, 2nd Edition, Cold Spring Harbor Laboratory Press,
  224. New York, USA.
  225. SAS (2002). Statistical Analysis System. SAS Institute Inc., Cary, North
  226. Carolina, USA.
  227. Sasaki K, Mitsumoto M (2004). Questionnaire-based study on consumer
  228. requirements for beef quality in Japan. Anim. Sci. J. 75: 369-376.
  229. Schenkel FS, Miller SP, Ye X, Moore SS, Nkrumah JD, Li C, Yu J,
  230. Mandell IB, Wilton JW, Williams JL (2005). Association of single
  231. nucleotide polymorphisms in the leptin gene with carcass and meat
  232. quality traits of beef cattle. J. Anim Sci 83: 2009-2020.
  233. Seaton G, Haley CS, Knott SA, Kearsey M, Visscher PM (2002). QTL
  234. express: mapping quantitative trait loci in simple and complex pedigrees.
  235. Bioinformatics 18: 339-340.
  236. Spelman RJ, Coppieters WL, Karim A, van Arendok JAM, Bovenhuis H
  237. (1996). Quantitative trait loci analysis for five milk production traits on
  238. chromosome six in the Dutch Holstein-Friesian population. Genet.
  239. 144: 1799-1808.
  240. Stone RT, Casas E, Smith TPL, Keele JW, Harhay G, Bennett GL,
  241. Koohmaraie M, Wheeler TL, Shackelford SD, Snelling WM (2005).
  242. Identification of genetic markers for fat deposition and meat tenderness
  243. on bovine chromosome 5: Development of a low-density single nucleotide polymorphism map. J. Anim. Sci. 83: 2280-2288.
  244. Stone RT, Keele JW, Shackleford SD, Kappes SM, Koohmaraie M
  245. (1999). A primary screen of the bovine genome for quantitative trait
  246. loci affecting carcass and growth traits. J. Anim. Sci. 77: 1379-1384.
  247. Tambasco DD, Paz CC, Tambasco-Studart M, Pereira AP, Alencar MM,
  248. Freitas AR, Coutinho LL, Packer IU, Regitano LCA (2003). Candidate
  249. genes for growth traits in beef cattle crosses Bos taurus x Bos indicus.
  250. J. Anim. Breed. Genet. 120: 51-56.
  251. Van Eenennaam AL, Li J, Thallman RM, Quaas RL, Dikeman ME, Gill
  252. CA, Franke DE, Thomas MG (2007). Validation of commercial DNA
  253. tests for quantitative beef quality traits. J. Anim. Sci. 85:891-900.
  254. Vilkki HJ, de Koning DJ, Elo KT, Velmala RJ, Maki-Tanila AV (1997).
  255. Multiple marker mapping of quantitative trait loci of Finnish dairy
  256. cattle by regression. J. Dairy Sci. 73: 2525-2537.
  257. White SN, Casas E, Allan MF, Keele JW, Snelling WM, Wheeler TL,
  258. Shackelford SD, M. Koohmaraie M, Smith TPL (2007). Beef cattle
  259. evaluation of six DNA markers developed for dairy traits reveals an
  260. osteopontin polymorphism is associated with postweaning growth. J.
  261. Anim. Sci. 85:1–10.
  262. White SN, Casas E, Wheeler TL, Shackelford SD, Koohmaraie M, Riley
  263. DG, Chase Jr. CC, Johnson DD, Keele JW, Smith TPL (2005). A
  264. new single nucleotide polymorphism in CAPN1 extends the current
  265. tenderness marker test to include cattle of Bos indicus, Bos taurus
  266. and crossbred descent. J. Anim. Sci. 83: 2001-2008." name="eprints.referencetext" />
  267. <meta content="Malau-Aduli, A.E.O. and Niibayashi, T. and Kojima, T. and Oshima, K. and Mizoguchi, Y. and Komatsu, M. (2007) Detection and mapping of QTL on bovine chromosomes 2 and 5 segregating for live weight, average daily gain and body measurements in Japanese Black Cattle. Journal of Cell and Animal Biology, 1 (3). pp. 034-043. ISSN 1996-0867" name="eprints.citation" />
  268. <meta content="http://eprints.utas.edu.au/3083/2/Malau-Adulietal2007JCAB.pdf" name="eprints.document_url" />
  269. <link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" />
  270. <meta content="Detection and mapping of QTL on bovine
  271. chromosomes 2 and 5 segregating for live weight,
  272. average daily gain and body measurements in
  273. Japanese Black Cattle" name="DC.title" />
  274. <meta content="Malau-Aduli, A.E.O." name="DC.creator" />
  275. <meta content="Niibayashi, T." name="DC.creator" />
  276. <meta content="Kojima, T." name="DC.creator" />
  277. <meta content="Oshima, K." name="DC.creator" />
  278. <meta content="Mizoguchi, Y." name="DC.creator" />
  279. <meta content="Komatsu, M." name="DC.creator" />
  280. <meta content="270200 Genetics" name="DC.subject" />
  281. <meta content="270207 Quantitative Genetics" name="DC.subject" />
  282. <meta content="300401 Animal Breeding" name="DC.subject" />
  283. <meta content="270208 Molecular Evolution" name="DC.subject" />
  284. <meta content="300406 Animal Growth and Development" name="DC.subject" />
  285. <meta content="300400 Animal Production" name="DC.subject" />
  286. <meta content="270800 Biotechnology" name="DC.subject" />
  287. <meta content="Bovine chromosomes 2 (BTA2) and 5 (BTA5) of purebred, half-sib progeny sired by five Japanese black
  288. bulls were genotyped using microsatellite DNA markers. The data were subjected to linkage analysis for
  289. the detection and mapping of segregating quantitative trait loci (QTL) influencing live weight, average
  290. daily gain and body measurements at weaning. Probability coefficients of inheriting allele 1 or 2 from the
  291. sire at specific chromosomal intervals were computed. The phenotypic data on progeny were regressed on
  292. these probability coefficients in a within-common-parent regression analysis. Fixed effects of sex, parity
  293. and season of birth as well as age as a covariate, were fitted in a linear model to the phenotypic data and
  294. subsequently analysed using QTL Express by generating an F-statistic through permutation tests at
  295. chromosome-wide significance thresholds over 10, 000 iterations at 1 cM intervals. Highly significant
  296. (P<0.01) segregating QTL for body measurements were detected on BTA2 for hip width (1 cM) and chest
  297. depth (8 cM) in Sire Family 1 and pin bone width (16 cM) in Sire Family 3. Other significant QTL (P<0.05)
  298. detected were withers height (3 cM), hip height (4 cM), body length (4 cM), shoulder width (6 cM), lumbar
  299. width (3 cM), thurl width (3 cM) and canon circumference (2 cM) in Sire Family 1, shoulder width (16 cM) in
  300. Sire Family 3 and thurl width (24 cM), pin bone width (19 cM), heart girth (26 cM) and abdominal width (69
  301. cM) in Sire Family 4. Significant (P<0.05) QTL for live weight and average daily gain were detected on BTA2
  302. for birth weight (5 cM) and weaning weight (3 cM) in Sire Family 1 and post-weaning average daily gain (68
  303. cM) in Sire Family 4. BTA 5 contained QTL for birth weight, pin bone width and heart girth in Sire Family 3
  304. that were only suggestive and not significant. Such localization of economically important QTL as
  305. demonstrated in this study, will expedite genetic improvement via marker-assisted selection, gene
  306. introgression and positional cloning in Japanese black cattle." name="DC.description" />
  307. <meta content="2007" name="DC.date" />
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  313. <meta content="Malau-Aduli, A.E.O. and Niibayashi, T. and Kojima, T. and Oshima, K. and Mizoguchi, Y. and Komatsu, M. (2007) Detection and mapping of QTL on bovine chromosomes 2 and 5 segregating for live weight, average daily gain and body measurements in Japanese Black Cattle. Journal of Cell and Animal Biology, 1 (3). pp. 034-043. ISSN 1996-0867" name="DC.identifier" />
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  418. <h1 class="ep_tm_pagetitle">Detection and mapping of QTL on bovine chromosomes 2 and 5 segregating for live weight, average daily gain and body measurements in Japanese Black Cattle</h1>
  419. <p style="margin-bottom: 1em" class="not_ep_block"><span class="person_name">Malau-Aduli, A.E.O.</span> and <span class="person_name">Niibayashi, T.</span> and <span class="person_name">Kojima, T.</span> and <span class="person_name">Oshima, K.</span> and <span class="person_name">Mizoguchi, Y.</span> and <span class="person_name">Komatsu, M.</span> (2007) <xhtml:em>Detection and mapping of QTL on bovine chromosomes 2 and 5 segregating for live weight, average daily gain and body measurements in Japanese Black Cattle.</xhtml:em> Journal of Cell and Animal Biology, 1 (3). pp. 034-043. ISSN 1996-0867</p><p style="margin-bottom: 1em" class="not_ep_block"></p><table style="margin-bottom: 1em" class="not_ep_block"><tr><td valign="top" style="text-align:center"><a onmouseover="EPJS_ShowPreview( event, 'doc_preview_4231' );" href="http://eprints.utas.edu.au/3083/2/Malau-Adulietal2007JCAB.pdf" onmouseout="EPJS_HidePreview( event, 'doc_preview_4231' );"><img alt="[img]" src="http://eprints.utas.edu.au/style/images/fileicons/application_pdf.png" class="ep_doc_icon" border="0" /></a><div class="ep_preview" id="doc_preview_4231"><table><tr><td><img alt="" src="http://eprints.utas.edu.au/3083/thumbnails/2/preview.png" class="ep_preview_image" border="0" /><div class="ep_preview_title">Preview</div></td></tr></table></div></td><td valign="top"><a href="http://eprints.utas.edu.au/3083/2/Malau-Adulietal2007JCAB.pdf"><span class="ep_document_citation">PDF</span></a> - Requires a PDF viewer<br />205Kb</td></tr></table><p style="margin-bottom: 1em" class="not_ep_block">Official URL: <a href="http://www.academicjournals.org/JCAB/contents/2007cont/Oct.htm">http://www.academicjournals.org/JCAB/contents/2007cont/Oct.htm</a></p><div class="not_ep_block"><h2>Abstract</h2><p style="padding-bottom: 16px; text-align: left; margin: 1em auto 0em auto">Bovine chromosomes 2 (BTA2) and 5 (BTA5) of purebred, half-sib progeny sired by five Japanese black&#13;
  420. bulls were genotyped using microsatellite DNA markers. The data were subjected to linkage analysis for&#13;
  421. the detection and mapping of segregating quantitative trait loci (QTL) influencing live weight, average&#13;
  422. daily gain and body measurements at weaning. Probability coefficients of inheriting allele 1 or 2 from the&#13;
  423. sire at specific chromosomal intervals were computed. The phenotypic data on progeny were regressed on&#13;
  424. these probability coefficients in a within-common-parent regression analysis. Fixed effects of sex, parity&#13;
  425. and season of birth as well as age as a covariate, were fitted in a linear model to the phenotypic data and&#13;
  426. subsequently analysed using QTL Express by generating an F-statistic through permutation tests at&#13;
  427. chromosome-wide significance thresholds over 10, 000 iterations at 1 cM intervals. Highly significant&#13;
  428. (P&lt;0.01) segregating QTL for body measurements were detected on BTA2 for hip width (1 cM) and chest&#13;
  429. depth (8 cM) in Sire Family 1 and pin bone width (16 cM) in Sire Family 3. Other significant QTL (P&lt;0.05)&#13;
  430. detected were withers height (3 cM), hip height (4 cM), body length (4 cM), shoulder width (6 cM), lumbar&#13;
  431. width (3 cM), thurl width (3 cM) and canon circumference (2 cM) in Sire Family 1, shoulder width (16 cM) in&#13;
  432. Sire Family 3 and thurl width (24 cM), pin bone width (19 cM), heart girth (26 cM) and abdominal width (69&#13;
  433. cM) in Sire Family 4. Significant (P&lt;0.05) QTL for live weight and average daily gain were detected on BTA2&#13;
  434. for birth weight (5 cM) and weaning weight (3 cM) in Sire Family 1 and post-weaning average daily gain (68&#13;
  435. cM) in Sire Family 4. BTA 5 contained QTL for birth weight, pin bone width and heart girth in Sire Family 3&#13;
  436. that were only suggestive and not significant. Such localization of economically important QTL as&#13;
  437. demonstrated in this study, will expedite genetic improvement via marker-assisted selection, gene&#13;
  438. introgression and positional cloning in Japanese black cattle.</p></div><table style="margin-bottom: 1em" cellpadding="3" class="not_ep_block" border="0"><tr><th valign="top" class="ep_row">Item Type:</th><td valign="top" class="ep_row">Article</td></tr><tr><th valign="top" class="ep_row">Keywords:</th><td valign="top" class="ep_row">QTL mapping, Japanese Black cattle, BTA2, BTA5, body measurements, live weight, daily gain.</td></tr><tr><th valign="top" class="ep_row">Subjects:</th><td valign="top" class="ep_row"><a href="http://eprints.utas.edu.au/view/subjects/270200.html">270000 Biological Sciences &gt; 270200 Genetics</a><br /><a href="http://eprints.utas.edu.au/view/subjects/270207.html">270000 Biological Sciences &gt; 270200 Genetics &gt; 270207 Quantitative Genetics</a><br /><a href="http://eprints.utas.edu.au/view/subjects/300401.html">300000 Agricultural, Veterinary and Environmental Sciences &gt; 300400 Animal Production &gt; 300401 Animal Breeding</a><br /><a href="http://eprints.utas.edu.au/view/subjects/270208.html">270000 Biological Sciences &gt; 270200 Genetics &gt; 270208 Molecular Evolution</a><br /><a href="http://eprints.utas.edu.au/view/subjects/300406.html">300000 Agricultural, Veterinary and Environmental Sciences &gt; 300400 Animal Production &gt; 300406 Animal Growth and Development</a><br /><a href="http://eprints.utas.edu.au/view/subjects/300400.html">300000 Agricultural, Veterinary and Environmental Sciences &gt; 300400 Animal Production</a><br /><a href="http://eprints.utas.edu.au/view/subjects/270800.html">270000 Biological Sciences &gt; 270800 Biotechnology</a></td></tr><tr><th valign="top" class="ep_row">Collections:</th><td valign="top" class="ep_row">UNSPECIFIED</td></tr><tr><th valign="top" class="ep_row">ID Code:</th><td valign="top" class="ep_row">3083</td></tr><tr><th valign="top" class="ep_row">Deposited By:</th><td valign="top" class="ep_row"><span class="ep_name_citation"><span class="person_name">Dr Aduli E.O. Malau-Aduli</span></span></td></tr><tr><th valign="top" class="ep_row">Deposited On:</th><td valign="top" class="ep_row">23 Jan 2008 13:45</td></tr><tr><th valign="top" class="ep_row">Last Modified:</th><td valign="top" class="ep_row">24 Jan 2008 11:02</td></tr><tr><th valign="top" class="ep_row">ePrint Statistics:</th><td valign="top" class="ep_row"><a target="ePrintStats" href="/es/index.php?action=show_detail_eprint;id=3083;">View statistics for this ePrint</a></td></tr></table><p align="right">Repository Staff Only: <a href="http://eprints.utas.edu.au/cgi/users/home?screen=EPrint::View&amp;eprintid=3083">item control page</a></p>
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